Transdermal Patch Manufacturing
Transdermal Patch Manufacturing is the production of transdermal patches. Transdermal Patches deliver drugs non-invasively from the surface of skin to the circulatory system (this is what is known as Transdermal Drug Delivery System – TDDS). A transdermal patch is a medicated patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.
The transdermal patch manufacturing process is composed of several steps, including formulation, mixing, coating, drying, lamination, converting, and packaging. The equipment used in these functions includes a combination of isolators, mixers, coaters, web lines, ovens, lamination, converting, and packaging equipment.
Who can call themselves a transdermal patch manufacturer?
A transdermal patch manufacturer is someone who is in the process of manufacturing transdermal patches.
The patches manufactured by ACT are either OTC patches or nutraceutical patches. In neither case are our customers claiming to deliver drugs. Therefore, because we are very careful with our words, we don’t claim to be a transdermal manufacturer. Please read more here.
We call our company a topical patch manufacturer. A custom contract topical patch manufacturer.
Transdermal patch manufacturers must not only consider the physical process of manufacturing, they must also adhere to federal and state regulations. These regulations include drug handling, testing, recalls, and environmental concerns, among others. Topical patch manufacturers, like ourselves, have to comply with many – but not all – of these strictures. (The handling of fentanyl, for example, is not something we are permitted to do).
When we manufacture OTC patches, we comply with all relevant FDA regulations. As a nutraceutical patch manufacturer, we are registered with both the FDA and state of California as a cosmetic manufacturer. (Non-OTC topical patches are categorized as cosmetics).
Advantages of transdermal delivery systems (TDD/TDDS):
Transdermal drug delivery (TDD) offers a number of advantages to the pharmaceutical industry. This method of delivery is patient- and caregiver-friendly due to its simple method of self-administration. It is painless and noninvasive, and for patients with serious or chronic conditions, it offers an easy way to take one less pill each day. Transdermal delivery also offers several advantages in compliance, as sustained-release patches can deliver a drug for up to 7 days, and the patch’s presence provides visual confirmation for patients or caregivers that the drug is being delivered (as opposed to having to wonder or try to remember if a pill was swallowed).
In terms of efficacy, administration of a drug via transdermal delivery allows the opportunity to avoid the first-pass metabolism of the drug in the liver. An additional advantage of transdermal delivery is the opportunity to reduce the chance of side effects, which can come from gastrointestinal exposure. Use of a patch also maintains constant therapeutic drug levels. Finally, an additional safety benefit provided by transdermal delivery is that it enables quick removal of the drug source in the event it becomes necessary.
Examples of true Transdermal Patches:
- Birth Control Patches
- Nicotine Patches
- Fentanyl Patches
Examples of Topical Patches, regardless of labeling:
- Menthol Patches
- Nutraceutical Patches
- Vitamin Patches
- CBD Patches
- Herbal Patches
If you are looking for a patch manufacturer who delivers top-quality patches designed to work, please give us a call. We would love to work with you! We’ve been in business since 1998, and we’re experts.